Yan Lu Selected Research

Matrix Metalloproteinases (MMPs)

10/2019	Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK II/ERK/NF-κB signaling pathway.
7/2017	The protective effect of propofol against TNF-α-induced apoptosis was mediated via inhibiting iNOS/NO production and maintaining intracellular Ca2+ homeostasis in mouse hippocampal HT22 cells.
7/2016	Distribution and clinical significance of circulating tumor cells in nasopharyngeal carcinoma.
1/2015	Upregulation of EMMPRIN (OX47) in Rat Dorsal Root Ganglion Contributes to the Development of Mechanical Allodynia after Nerve Injury.
11/2013	Clinicopathologic significance of claudin-6, occludin, and matrix metalloproteinases -2 expression in ovarian carcinoma.
5/2012	Mechanisms mediating propofol protection of pulmonary epithelial cells against lipopolysaccharide-induced cell death.
4/2009	Mice deficient in PKCbeta and apolipoprotein E display decreased atherosclerosis.
3/2007	The role of ROS in microcystin-LR-induced hepatocyte apoptosis and liver injury in mice.

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Yan Lu Research Topics

Disease

220	Neoplasms (Cancer) 05/2024 - 01/2000
78	Inflammation (Inflammations) 05/2024 - 05/2002
38	Infections 02/2024 - 08/2003
34	Neoplasm Metastasis (Metastasis) 02/2024 - 01/2010
31	Non-alcoholic Fatty Liver Disease 02/2024 - 05/2013
29	Carcinogenesis 11/2023 - 02/2006
28	Breast Neoplasms (Breast Cancer) 10/2022 - 02/2011
25	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 08/2007
24	Lung Neoplasms (Lung Cancer) 11/2023 - 02/2006
24	Melanoma (Melanoma, Malignant) 10/2023 - 08/2006
23	Pain (Aches) 01/2024 - 01/2008
22	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 11/2012
22	Body Weight (Weight, Body) 11/2023 - 04/2004
22	Hypertension (High Blood Pressure) 01/2023 - 04/2013
21	Insulin Resistance 01/2023 - 02/2008
20	Wounds and Injuries (Trauma) 02/2024 - 10/2010
20	Acute Lung Injury 01/2024 - 08/2010
20	Type 2 Diabetes Mellitus (MODY) 08/2023 - 03/2006
19	Fibrosis (Cirrhosis) 12/2023 - 09/2002
18	Obesity 08/2023 - 08/2011
17	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 05/2009
16	Atherosclerosis 11/2023 - 05/2002
16	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2022 - 09/2013
15	Stroke (Strokes) 01/2024 - 11/2009
15	Reperfusion Injury 01/2024 - 02/2004
15	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023 - 04/2018
14	Carcinoma (Carcinomatosis) 01/2024 - 01/2000
14	Hypoxia (Hypoxemia) 01/2024 - 08/2006
12	Ischemia 10/2023 - 02/2004
12	Stomach Neoplasms (Stomach Cancer) 10/2023 - 01/2005
12	Fatty Liver 11/2022 - 08/2014
12	Brain Ischemia (Cerebral Ischemia) 01/2021 - 12/2008
11	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 01/2012
11	Ovarian Neoplasms (Ovarian Cancer) 11/2023 - 11/2013
11	Myocardial Infarction 10/2023 - 12/2010
11	Infarction (Infarctions) 01/2023 - 04/2008
11	Leukemia 01/2021 - 12/2002
11	Necrosis 09/2020 - 07/2003
11	Hyperplasia 01/2018 - 09/2002
10	Cognitive Dysfunction 05/2024 - 02/2015
10	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 03/2011
10	Myocardial Ischemia (Ischemic Heart Diseases) 01/2024 - 08/2004
10	Parkinson Disease (Parkinson's Disease) 06/2023 - 12/2008
10	Hyperglycemia 01/2021 - 06/2005
9	Vitiligo 05/2024 - 02/2015
9	Sepsis (Septicemia) 04/2023 - 02/2009
8	Pneumonia (Pneumonitis) 01/2024 - 05/2018

Drug/Important Bio-Agent (IBA)

108	Proteins (Proteins, Gene)FDA Link 04/2024 - 10/2004
61	Biomarkers (Surrogate Marker)IBA 03/2024 - 06/2006
36	RNA (Ribonucleic Acid)IBA 12/2023 - 11/2011
31	CytokinesIBA 12/2023 - 05/2008
30	LipidsIBA 01/2024 - 04/2006
29	Messenger RNA (mRNA)IBA 12/2023 - 07/2006
25	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 04/2010
25	MicroRNAs (MicroRNA)IBA 01/2024 - 02/2012
23	EnzymesIBA 01/2024 - 08/2004
23	Triglycerides (Triacylglycerol)IBA 12/2023 - 02/2011
19	AntigensIBA 03/2024 - 06/2007
19	Polysaccharides (Glycans)IBA 01/2024 - 06/2010
19	LigandsIBA 01/2022 - 05/2002
18	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 07/2007
18	Therapeutic UsesIBA 01/2024 - 07/2014
16	Long Noncoding RNAIBA 01/2024 - 10/2016
15	AcidsIBA 04/2024 - 08/2007
15	Phosphotransferases (Kinase)IBA 04/2024 - 07/2006
15	Interleukin-6 (Interleukin 6)IBA 01/2024 - 08/2011
15	Neuroprotective AgentsIBA 11/2023 - 12/2008
13	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2024 - 04/2013
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 04/2003
12	AntioxidantsIBA 11/2023 - 03/2007
12	Small Interfering RNA (siRNA)IBA 01/2021 - 10/2006
11	Transcription Factors (Transcription Factor)IBA 05/2024 - 02/2008
11	LipopolysaccharidesIBA 01/2024 - 02/2009
10	Retinaldehyde (Retinal)IBA 05/2024 - 08/2009
10	Ketamine FDA LinkGeneric 05/2024 - 12/2016
10	SteroidsIBA 09/2023 - 11/2009
10	CalciumIBA 05/2023 - 11/2005
10	Blood Glucose (Blood Sugar)IBA 01/2022 - 12/2009
10	Propofol (Diprivan)FDA LinkGeneric 01/2022 - 05/2012
10	Insulin (Novolin)FDA Link 01/2021 - 02/2008
10	ApolipoproteinsIBA 11/2013 - 05/2002
9	Indicators and Reagents (Reagents)IBA 03/2024 - 04/2013
9	Fatty Acids (Saturated Fatty Acids)IBA 01/2024 - 08/2006
9	Complement System Proteins (Complement)IBA 12/2023 - 02/2017
9	CateninsIBA 11/2023 - 01/2019
9	Circular RNAIBA 07/2023 - 01/2018
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 01/2000
9	CollagenIBA 01/2022 - 02/2008
9	claudin 6IBA 08/2019 - 08/2012
8	Anti-Bacterial Agents (Antibiotics)IBA 04/2024 - 06/2013
8	salicylhydroxamic acid (SHAM)IBA 01/2024 - 05/2004

Therapy/Procedure

101	Therapeutics 03/2024 - 01/2000
27	Drug Therapy (Chemotherapy) 03/2024 - 12/2006
18	Immunotherapy 12/2023 - 09/2003
16	Chinese Traditional Medicine (Traditional Chinese Medicine) 10/2023 - 01/2013
15	Lasers (Laser) 03/2023 - 07/2003
11	Aftercare (After-Treatment) 04/2023 - 04/2006
9	Castration 02/2024 - 09/2014
9	Electroacupuncture 06/2019 - 06/2009
8	Injections 05/2024 - 02/2008